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. Jeffery and his colleagues have isolated one of those master-control genes, a gene known as Hedgehog, or Hh, whose modified expression leads to blindness in cave fish
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. 8 A to those in Fig
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. Folding rates for two-state proteins show statistically significant correlation with native-state contact order (104)
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. These models have an ad hoc flavor and are anchored in Flory's random-coil paradigm, where local biases are modeled accurately and long-range interactions are either ignored or modeled using a mean field
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. coelicolor has been reported, and the corresponding proteins cloned and expressed (14-16)
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. 5 mM KCl, 1 mM CaCl^sub 2^, 1 mM MgCl^sub 2^, 1 mM Na^sub 2^HPO^sub 4^, 5 mM HEPES, pH 7
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. Cation-chromatin binding as shown by ion microscopy is essential for the structural integrity of chromosomes
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. RESULTS AND DISCUSSIONCharacterization of soluble prefibrillar aggregates and protofibrilsGeneration of prefibrillar oligomers of TTR from the A-stateProlonged dialysis of TTR (96 h, 4°C) versus 10 m M HCl in dH^sub 2^O in the absence of salt (pH 2
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. 1 C was rapidly cooled to 5°C and scanned again from 5 to 100°C
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. According to the polymeric paradigm (Fändrich and Dobson, 2002) of amyloidogenesis and the therein-implicated importance of backbone interactions, the more the native structure becomes distorted (and the protein backbone becomes exposed), the higher the chance that the protein steps onto the amyloidogenic pathway
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. A total of 11 to 18 melanophores, about one melanophore per anal fin pterygiophore, was observed in postflexion larvae (Fig
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. Female black rockfish were primarily obtained from recreational charter boat landings in Newport, Depoe Bay, and Charleston, Oregon, in addition to some fish from commercial landings from Port Orford, Oregon (Fig
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. Conversely, pellets maintained in DMEM/10%FCS possessed limited extracellular matrix (Fig
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. Indeed, by the fourth block the advice group made no failure to hit errors (see Table 3)
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. Thus, to record adequate emission spectra for GR, we routinely started acquisition of the spectra at 295 nm (as shown in Fig
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. The dominant crosspeak in the asynchronous plot was a positive peak centered at (1629 cm^sup -1^, 1617 cm^sup -1^), whereas minor positive peaks could he found at (1648 cm^sup -1^, 1617 cm^sup -1^) and (1658 cm^sup -1^, 1617 cm^sup -1^)
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.CONCLUSIONCell death, removal, and replenishment are essential both to maintain homeostasis in the nondiseased organism and to appropriately regulate inflammation and tissue repair during disease
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