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He continued, no doubt in frustration, and fell back on a Lamarckian explanation: "It appears probable that disuse has been the main agent in rendering organs rudimentary
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Assisting the reactivation of guanidine hydrochloride-denatured aminoacylase by hydroxypropyl cyclodextrins
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Unfolding and refolding of porcine odorant binding protein in guanidinium hydrochloride: equilibrium studies at neutral pH
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Analysis of difference contact maps suggests that to fold, the dilatation symmetry in the EV limit is broken by weakening specific nonnative local contacts
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Am J Respir Crit Care Med 2004; 169:195-200(60) Yainaryo T, Oishi K, Yoshimine H, et al
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However, our data indicate that aggregation and in addition at least one of these other mechanisms seems to play a role for the α-amylases with red shifts upon thermal unfolding (i
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It has a 100% amino acid identity among all analyzed vertebrates, and plays a central role in translating intracellular Ca^sup 2+^ signals into biological responses
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07, and are fairly uniform throughout the sequence, except for five outliers with S^sup 2^^sub s^ values between 0
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Thus, the data are consistent with a motional model in which the two N-terminal and two C-terminal CaM domains in the dimeric CaM:SEF2-lmp complex undergo a small-scale wobbling motion with a half-angle of ~20° as estimated from S^sup 2^^sub s^ = 0
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, when the CaM:SEF2-1mp interaction brakes, one side of the CaM dimer interaction also momentarily brakes
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The most important studies on DNA-monocation binding are summarized in Table 1, which shows the activity sequences, methods used in research, and the corresponding citations in our list of references
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Activation of PLCβ by G-protein subunits thus appears to occur through lateral association of the membrane-bound species
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The exponentially large search times arise transparently from the factor (R/R^sub N^)^sup (d-2)^ in Eq
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Ratiometric single-molecule studies of freely diffusing biomolecules
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- Of that figure, nearly $15 million came from EPS bonuses
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. For example, at 20 µm ANS where binding sites are fully saturated in solution and the intensity has reached its maximum value, the corresponding intensity in ice is merely 3%-5% of the value in the liquid water
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. Therefore, in this case, R-type flux having solder-flux interfacial tension 445 mN/mm (which is higher than the other two fluxes) contributes to the lower values of γ^sub LF^ - γ^sub SL^ and is attributed to the higher contact angles and negative wetting forces (Fig
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. The peptide still interacts with the same exposed hydrophobic patches as in the wraparound binding mode, but here a number of weak interactions occur instead of one strong
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. Note that potential variation of the ^sup 15^N CSA between -150 and -200 ppm hardly affects RT^sup n^^sub 1^ (±3%), and thus does not affect the conclusions (22)
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