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Yeast GR presents a quite blue-shifted fluorescence emission spectrum (maximal emission wavelength at 317 nm for the native protein; see Fig
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Hence, one must be cautious in interpreting observations of nuclear Overhauser effects as evidence for residual, long-range structure in highly denatured states
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The CaM dimer is created by the tip of the N-terminal domain of one CaM monomer contacting the tip of the C-terminal domain of the other CaM
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In FAP, mutants of TTR misfold and form amyloid deposits in peripheral nerves, causing peripheral neuropathy
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The misfolding and aggregation reaction as monitored by chemical cross-linking (Fig
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Standard techniques for pelagic fish egg and larva surveys
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MATERIALS AND METHODSRNA constructs2'-0-bis(2-acetoxyethoxy)methyl orthoester (2'-ACE) protected RNA strands were purchased from Dharmacon (Boulder, CO)
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By contrast, limited type-II collagen staining was apparent in the pellets maintained in DMEM/10%FCS (Fig
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