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It's not been a problem, anyway
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From the changes in the fluorescence intensity, the apparent pK^sub a^ of the titration was 4
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Depending on the kind of denaturing conditions (high salt concentrations, extreme pH, elevated temperatures, pressure, etc
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4, we show that Gα^sub s^ is destabilized under pressure even at relatively high lipid concentrations, although we note that membrane binding of Gα^sub s^ is weaker than Gβγ (i
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This is not yet reachable for proteins with the current computation timescale of nanoseconds
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The gp120 molecule without the V3 loop and the CD4 molecule, both using all atoms (code: all) or using only backbone (N, Cα, and C') atoms (code: bb); see Fig
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It is, however, not obvious to explain the slight, unexpected gain in entropy upon complexation for gp120 (Fig
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In the simulations, the interconversion rate constants are defined in comparison with an experimental reference time
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4146#Naproxen ect & sr0
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