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At first glance, these results are surprising since the highly denatured state is the starting point for in vitro folding reactions and yet no consideration of the denatured-state topology is required to account for the folding rates
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Mutational analysis demonstrates that specific electrostatic interactions can play a key role in the denatured ensembles of proteins
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Experiments between pH 4 and 5
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We hypothesize that this compensatory effect could be due to a change in the coordination sphere of the Mg^sup 2+^ by directly involving the phosphoryl group of the PEP moiety, as it occurs in a member of the pyruvate dikinase family (57)
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(32) The first pathway includes UNC-73, MIG-2, ced-12, ced-5, and ced-2 (representing the mammalian homologues TRIO, RhoG, ELMO, Dock 180, and CrkII, respectively)
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Evidence for binding of rose bengal and anilinonaphthalenesulfonates at the active site regions of liver alcohol dehydrogenase
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This novel mode of target-specific binding, which neither belongs to lock-and-key nor induced-fit binding, is characterized by dimerization and continuous exchange between multiple flexible binding alternatives
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The lower platen consisted of a Peltier temperature control surface
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As the associated shear stress was [much less than]50 kPa, we ascribe this behavior to being equivalent to the η^sub 0^ of hard sphere colloidal suspensions
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, 1983) for necessary charge neutralization
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The simplest explanation is that GDP-bound Gα^sub s^-subunits bind to Gβγ, but not necessarily at its primary interaction site
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The chains are connected by two disulfide bridges: A7-B7 and A20-B19, whereas a third bridge binds cysteine residues 6 and 11 of the A-chain (e
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These differences were not statistically significant (p > 0
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Effect of transforming growth factor-beta 1 (TGF-beta 1) on matrix synthesis by monolayer cultures of rabbit articular chondrocytes during the dedifferentiation process
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In other words, they might substitute relatively costly analgesic drugs, including various opiates, that are not subject to PP for those that are
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In addition to sharing and discussing the article with r students, be mindful that parents and other adults should use prescription drugs as directed, then discard any leftover pills
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