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In spite of its harmful effects, the gene persists among human populations in parts of Africa with a high incidence of malaria
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Part of this deformation includes the bones of the nose
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This solution was then dialyzed against 1
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Specifically, we believe that ensembles for proteins obtained in the EV limit (48,124-127), will have characteristics that match predictions from field theories
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Phenylalanine side chain behavior of the intestinal fatty acid-binding protein: the effect of urea on backbone and side chain stability
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The trypsin pmtcomics grade was from Sigma
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(13,16,38) The suppressive effect of efferocytosis on the adaptive immune system appears to be largely PS-dependent, to include both TGF-[beta]1-dependent and TGF-[beta] 1-independent mechanisms, and to result in decreased antigen-specific CD4 T cells, antigen-specific IgG, dendritic cell maturation, and IL-12 production
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On the other hand, different n values seem to correlate with the large disparity in internal hydration and structural flexibility among the three mutant azurins
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This approach was aimed at acquiring compartment-specific spectra of an oocyte and at monitoring drug uptake into its subcellular compartments
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1 A shows the ^sup 1^H MR image of a single cell, a stage VI X
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It should be noted that the diminazene aceturate concentration we used for the cellular uptake experiment is relatively high (250 mM) but still not even half a percent of the concentration of water which dominates the MR signal
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0, when the protein carries a net negative charge, can be described by hard sphere behavior those at pH 3
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The time course of the protein unfolding, which was triggered by a rapid increase in the Gdm HCl concentration from 0 to 1-6 M, was monitored by CD at 222 nm (Fig
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11 mi north of Reading, Penn Township, Berks County, PA
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International Conservation of Bird Preservation Technical Publication 5
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The world presents a vast patchwork of NSAID usage
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Because tumors grow faster than their blood supply, their centers usually lack oxygen
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During a presentation on trends, issues and forecasts for the pharmaceutical industry in 2004 and beyond, Long said that when a generic drug hits the market today, it captures 70 percent of new prescriptions within four weeks
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Pharmacy reps voice anger over Medicare Part B shiftsJames FrederickBALTIMORE -- Frustration over dwindling reimbursements for prescriptions filled under theMedicare Part B program boiled over last month, with pharmacy leaders voicing anger at a confusing Part B fee schedule that's being scrambled by a shifting payment model and the launch of Part D drug benefits
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Stress at college: Effects on health habits, health status and self-esteem
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Compiled by Heather Gunter, hgunter@advanstar
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Thus, an individual's primary underlying driving force could be indicative of both their level and frequency of gambling involvement
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A Test Pilot School graduate, he has over 160 hour, in the Osprey
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The program followed the game of blackjack as played in casinos but with some simplifications (there was no provision for splitting, doubling, or insurance, nor were standoffs possible when the player drew blackjack)
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The illusion of control
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Fear of busting (going over 21) was common
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However, in a simplification of the rules, there was no provision for splitting, doubling, and insurance, and standoffs were not allowed when the player drew blackjack
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. Both of these states are characterized by expanded hydrodynamic radii, loosening of tertiary structure, and preservation of secondary structure
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. Similarly to that observed for EIC^sup ec^, the electrostatic, as well as the van der Waals interactions, were decreased in EIC^sup sc^, losing several salt bridges and hydrogen bonds when compared with the structure of EIC^sup tt^
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. A possible explanation for this large red shift during thermal unfolding, which is almost as large as those obtained with GndHCl-induced unfolding (see Table 2), may be given by the fact that the absent aggregation gives rise to only a weak burial of tryptophan residues
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. We interpret this such that aceturate experiences faster diffusion in the nucleus than in the macromolecule-rich animal cytoplasm and that, although there is no strong macromolecule-binding of aceturate molecules, they are nonetheless restricted in their translational and rotational motions, which would result in a short spin-spin relaxation time and a correspondingly large linewidth
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. The protein purity assessed by SDS gel electrophoresis was 95%
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. Recently, ideas as to the generic, polymeric character of amyloids (Fändrich and Dobson, 2002), and the importance of destabilization (or complete unfolding-e
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. The crossing-over of the complex and free buildup curves at ~6 ns (Fig
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. In other words, the second MD trajectory segment covers a small subspace of the conformational space sampled by the first segment and hence reduces the overall size of the elements of the covariance matrix σ through averaging over the combined trajectories
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. Reproduction, embryonic energetics, and the maternal-fetal relationship in the viviparous genus Sebastes (Pisces: Scorpaenidae)
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