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. Decreased apoptosis and increased activation of alveolar neutrophils in bacterial pneumonia
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. Quantitative estimation of protein binding site polarity
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. Consequently, MR spectra obtained with sufficient SNR from the nucleus can be expected to reflect both the transport into the nucleus and the DNA binding of the drug
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. CONCLUSION In vivo localized MR spectra were recorded from subcellular regions within X
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. Solvent stabilization by salting-out ions is a consequence of a decrease in free energy of the native state, due to both entropic and enthalpic contributions; in particular, the effect on hydration water is expected to be mainly entropic, whereas the observed decrease in protein MSDs (44) indicates a tighter packing of the apolar residues in the core of the protein as suggested for hydrophobic stabilization by calorimetry experiments (59)
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. 3 is achieved when only the average (τ^sup o^^sub m^)^sub app^ in the helices are considered
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. For colloidal systems, the initial effects of attraction, particularly at high volume fractions, is a reduction in viscosity as the initial clustering of particles increases the free volume available for structural rearrangement (1)
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. Human carbonic anhydrase II is considerably expanded by the interaction of GroEL
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. Taken together, these data indicate that heating of the apoA-2:DMPC disks to 99°C leads to protein unfolding and disk-to-vesicle fusion; consecutive cooling leads to a gradual reduction in the vesicle size and partial protein refolding, followed by formation of smaller protein-containing vesicles and additional helical refolding at 34-24°C
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. Concomitantly, the third hypervariable loop (V3) undergoes a rearrangement to a somewhat different conformation leading to accessibility of the epitope for co-receptor binding
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. eduManuscript submitted 13 March 2003 to Scientific Editor's Office
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- Of that figure, nearly $15 million came from EPS bonuses
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. None of these models can provide an accurate description of conformational ensembles accessible to highly denatured proteins since they explicitly disregard the effects of correlated fluctuations imposed by two-body EV interactions
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. coelicolor, first, to understand in depth the mechanism of the PTS; and, second, to provide new clues on the protein folding problem
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. Pig pancreas α-amylase (PPA
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. As a consequence the corresponding emission spectra that were measured during unfolding appear completely different (Fig
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. A study of diffusion isotropy in single neurons by using NMR microscopy
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. Berenil [1,3-bis(4'-amidinophenyl)triazene] binding to DNA duplexes and to a RNA duplex: evidence for both intercalative and minor groove binding properties
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. A 45% decrease in activity was recorded after the neutron scattering experiment
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.Osmotic stress techniqueThe dependence of the osmotic pressure of BLG solutions on protein concentration, pH, and added NaCl concentration was determined using an osmotic stress technique
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. DNA compaction under such conditions can be considered as a model of DNA compaction in the protein-crowded environment inside living cells
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. Fibril in senile systemic amyloidosis is derived from normal transthyretin
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. The polymer solution was poured into a dynamic light scattering (DLS) cell and cooled for 1 hour at 25°C
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. Folding of the hairpin ribozyme in its natural conformation achieves close physical proximity of the loops
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. Correlating structural dynamics and function in single ribozyme molecules
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.HX-21 covers the entire spectrum of ordnance related operations
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. This kind of play can be considered irrational, because it is suboptimal from the perspective of the probabilistic models
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