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. Control experiments revealed a similar increase in thiol reactivity in the presence of 1 M KCl (data not shown)
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. coli GR and yeast GR
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. Thus the β-sheet on the surface of the catalytic domain, Which is exposed to water in native ACYI, might unfold first
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. 8 C suggest that the "observed" correlation between m values and ΔC^sub P^ to changes in solvent-accessible surface area might in fact be serendipitous
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. Other characteristics considered important included "energy" checked off by 36%, "digestive health" by 35% and "immunity enhancement" by 24%
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. Our approach suggests that thermodynamical analysis might reveal subtle conformational changes
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. Steady-state ANS binding ANS binding was detected by collecting fluorescence spectra at different pH in the presence of 100 µM of dye
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. These small changes upon binding of the effectors were also monitored by the changes in the accessibility of fluorescent residues and the trypsin digestion patterns
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. The Saccharomyces cerevisiae nucleoporin Nup2p is a natively unfolded protein
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. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-[beta]1 secretion and the resolution of inflammation
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. This study was designed to evaluate the potential of localized MR spectroscopy to investigate subcellular phenomena
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. For instance, the barnase (45) and oxalocrotonate tautomerase (46) bind specifically to their rigid target to form a specific complex with essentially one overall conformation
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. RESULTS AND DISCUSSIONCharacterization of soluble prefibrillar aggregates and protofibrilsGeneration of prefibrillar oligomers of TTR from the A-stateProlonged dialysis of TTR (96 h, 4°C) versus 10 m M HCl in dH^sub 2^O in the absence of salt (pH 2
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. This suggests different modes of lipid-protein interactions in plasma spherical and model discoidal HDL, which may result from different chemical composition and/or geometry of these particles
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. 8) n=20 PAL/BLx100ED/BLx100Preflexion53
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. , Liquid-liquid Phase Separation and Crystallization in Binary Polymer Systems, Polymer 28 (2), 193-200 (1987)
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. 1 M sodium cacodylate buffer containing 0
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.--Pharmaceutics Medicinal Chemistry Pharmacology Toxicology* UTAHUniversity of Utah College of Pharmacy Ph
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.Comparison in SLSI, PCS-12 and MCS- 12 scores by gender are presented in Table 2
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