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It is interesting to consider what the possible impact of FAD and NADPH would be on the folding of GR
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Our results also suggested that the usage of resolution-enhancing techniques could provide valuable information of the step-wise unfolding of proteins
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Control experiments were earned out at 7 M GdmHCl, pH 7, where the protein was fully unfolded
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The phosphotransferase system of Streptomyces coelicolor is biased for N-acetylglucosamine metabolism
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This collective process could explain the fact that essentially all resonances affected by conformational exchange have approximately the same time constant and are clustered in regions important for either CaM:CaM or CaM:SEF2-1mp interactions
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For AHS both approximate analytic (71) and recent machine calculations (20) indicate that to a very large extent the metastable liquid-liquid coexistence curve lies below the percolation line, and so particle gel formation rather than liquid-liquid separation is predicted
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An ion with a smaller radius corresponds to stronger hydration, and the hydrated radius sequence for monocations is Li+ > Na+ > K+ > Rb+ > Cs+
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Protein folding and misfolding
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How has such a remarkable reduction in folding time been achieved without the use of a spatially "funneled" energy landscape? Of course energetic interactions have been implied, but these have not been of the spatially-extended type
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, 2002a) in which the "transition state" strongly constraints the environment of just three residues and the immediate neighbors
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In contrast to the compact CD4, gp120 undergoes a number of significant loop contractions and translocations upon CD4 binding, which occur on a more extended timescale than the high-frequency local fluctuations
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The fabrics in this study are described in Table II
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Our data on T^sub g^ of the IPP polymers (9 to 13°C) are consistent with reference 3, which reported that the T^sub g^ of IPP polymer ranges from about -30 to +20°C and depends on tacticity and thermal history
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Samples for transmission electron microscopy were fixed in 0
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. The count of N-glycosylated proteins reported so far is 883, whereas O-glycosylated proteins only number 188
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