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This work was supported by grants from the Howard Hughes Medical Institute, The John Simon Guggenheim Memorial Foundation, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico, and Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro
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In the red blood cells of people carrying the gene, mutant hemoglobin molecules stick together to form rodlike bundles that deform the red blood cells into the shape of a sickle
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Not all the possible pleiotropic effects of Hh in cave fish are known, but suggestive scenarios abound
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The appearance of the unusual exothermic peak and the lack of endothermic peak suggested that the unfolding of ACYI was accompanied by serious aggregation, which might be a nucleation-dependent process (36)
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The IR and fluorescence results strongly suggested that the thermal unfolding of ACYI could be illustrated as a two-stage process involving an intermediate: native state (N) [arrow right] intermediate stale (I) [arrow right] aggregates (A)
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Covalently hound sugars in proteins range from small monosaccharides, especially on nuclear and cyloplasmic proteins, to substantially complex molecules on extracellular N- or O-linked glycoproteins, including many lectins
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How native-state topology affects the folding of dihydrofolate reductase and interleukin-1β
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The pronounced blue shift for native proteins in NDSB solutions is most probably related to the fact that NDSB interacts with the surface of the proteins which causes a more hydrophobic nonpolar environment of surface exposed tryptophan residues
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The qualitative structural implication is, therefore, that the second CaM monomer in the dimeric complex is placed along this axis in such a way that the tips of the N- and C-terminal domains touch each other
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They generally have k^sup -1^^sub ex^ values below 100 µs confirming the trend
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Surprisingly, the rank order for the disk stability indicated by our DSC, CD, and light-scattering data (Figs
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3-nm in diameter, with elongated features (Khurana et al
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Since the binders for these paper toners were based on styrene-acrylic copolymers, the printed fabric had extremely poor textile properties
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Journal of Social Psychology, 142, 405-424
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