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The proteins were redissolved in D^sub 2^O and centrifuged at 6000 × g for 10 min before use with a final pD of 8
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Spectra were collected from 30°C to 98°C at intervals of 2°C with a spectral resolution of 4 cm^sup -1^ and 256 scans
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If one were to examine chain properties at length scales that go above l^sub s^, properties of denatured proteins for different sequences should become indistinguishable from each other
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INTRODUCTIONCalmodulin (CaM) is a Ca^sup 2+^ binding protein, present in all eukaryotic cells
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A novel target recognition revealed by calmodulin in complex with the basic helix-loop-helix transcription factor SEF2-1/E2-2
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Fred Mellon for performing the mass spectrometry and Professor Lindsay Sawyer for advice on the literature
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These diseases include the amyloidoses such as Alzheimer's disease and familial amyloidotic polyneuropathy (FAP)
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Trans-suppression of misfolding in an amyloid disease
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5 B indicate that pressure does not promote the transition of PLCβ to an activated conformation
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Yet it is hard to escape from the deceptive simplicity of low-dimensional projections of folding funnels that appear necessarily in all graphical portrayals of it
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2]), was estimated from swept area
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The set of atoms is indicated by the code 2nd
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2 B), where a subspace of the conformational space of the free molecule is sampled in the complex state
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