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. 2, N is the number of residues, and R^sub ij^ is the distance between atoms i and j
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. we plot ln([left angle bracket]R^sub ij^[right angle bracket]) versus ln(|j - i|) for four representative sequences drawn from Table 1
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. Further, the model was evaluated with PROCHECK (37)
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. Misfolding and aggregation kinetics monitored by ANS, Bis-ANS, DCVJ, and ThTTime course changes accompanying TTR misfolding and aggregation were recorded to elucidate preferential fluorescence signals of the probes depending on the conformational state of the protein
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. If this idea is correct, then the volume associated with Gβγ activation of PLCβ corresponds to the difference in volume changes for PLCβ-Gβγ alone and in the presence of Gα^sub s^(GDP), ranging from ΔV ~3 to 15 ml/mol (Table 1)
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. Address reprint requests to Suzanne Scarlata, E-mail: Suzanne
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