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Cash made no excuses for what men had done to land them in hell, but neither did he vindicate the hell others t,ad made for them
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. Here we applied this method to analyze delta and gamma dispersions for protein solutions
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. Two-dimensional correlation sSpectroscopy: effect of hand position, width, and intension changes on correlation intensities
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. It is apparent that the role of glycosylation in maintaining conformational stability is more pronounced compared to regulating the ultimate functional form of the protein
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. 34 the chain is in a poor solvent and fomrs a compact globule by minimizing contacts with the surrounding solvent
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. Notwithstanding the relevance of the phenomenon, little is known of the structure of proteins in ice owing primarily to the inapplicability or the poor sensitivity of usual spectroscopic techniques in this highly scattering and anisotropic medium
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. For the drug uptake experiments, the oocyte was then immersed in an aqueous solution of 250 mM diminaze aceturate (Sigma) and inserted into the MR tube loaded with the same solution
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. This collective process could explain the fact that essentially all resonances affected by conformational exchange have approximately the same time constant and are clustered in regions important for either CaM:CaM or CaM:SEF2-1mp interactions
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. In comparison, the misfolded aggregated states from A-state TTR show a much stronger quantum yield for Bis-ANS than for ANS (Fig
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. 2) and transmission electron microscopy (Fig
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. , 3-15 ml/mol) volume element
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. Studies on insulin derivatives established that the two B-chain's termini might play distinct roles in the amyloidogenesis: the C-terminal slows down the process, whereas the residues at the N-terminal are necessary for the lateral aggregation, i
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. Radiation from nearby stars heats up molecular bonds in the cloud, breaking them apart and liberating atomic hydrogen
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. Using these simulations, we find that the shapes of the histograms are significantly altered by modest changes (twofold) in the interconversion rate constants or their ratio (equilibrium constant)
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. By contrast GAG levels were reduced by 25% over the same period for pellets maintained in DMEM/10%FCS
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- A reporter's e-mail exchange with Carter Center press secretary Deanna Congileo elicits the response that none of the anonymous donors are from the Middle East, but no further details can be released without permission from the donors--which, even if granted, will take some time to obtain (stay tuned)
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. The pentapeptide GGAGG has P^sub II^ conformation
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.3]- and [alpha]v[[beta]
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. This is in contrast with stabilization by kosmotropic buffers, which decrease the free energy of the native state
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