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With eyes and without eyes, a fish can see no more than you can in the perpetual darkness of a cave
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However, the low homology among the amino acid sequences of D- and L-aminoacylases available suggests that they may have different fold and catalytic mechanisms (2)
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Reversibility of the thermal transition was examined by reheating the samples after cooling from the first scan
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In the naive lung, demonstration of the death/ removal/replenishment cycle has been more elusive
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As a first step in this direction, we measured the thermal unfolding transition of α-amylases in the presence of NDSB, which is known to be an effective agent to prevent aggregation of thermal unfolded proteins (32-34)
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Several NMR variants additionally provide spatial information (2,3): Spatial maps of water protons, relaxation properties, diffusion or flow inside an animal or human body can be obtained with magnetic resonance imaging (MRI), and in vivo localized magnetic resonance spectroscopy (MRS) delivers chemical spectra at predefined regions of such samples
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Prefibrillar amyloidogenic oligomers and protofibrils of misfolded TTR were generated in vitro through induction of the molten globule type A-state from acid unfolded TTR through the addition of NaCl
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Mature human plasma HDL and LDL are also stabilized by kinetic barriers, suggesting that such barriers provide a universal natural strategy for lipoprotein stabilization (Mehta et al
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Although newly-formed oligomers initially retain nativelike structure (Bouchard et al
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We observed a recurring trend of older, larger fish extruding larvae earlier in the reproductive season and larval output being increasingly dominated by younger and younger fish
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Taking risks: The relationship of impulsivity, sensation seeking, stress-coping, and substance use in youth gamblers
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96) was too small to have any substantial impact on the players' behavior
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