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. The models were constructed with the SWISS MODEL server (33) by using the structures of EIN^sup ec^ (PDB accession code IZYM) and EIC^sup tt^ (PDB accession code 2BG5) as templates
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. On a molar basis, the greatest apparent affinity and the largest values of H are exhibited by the tetramers LDH, YADH, and ALD, the smallest by the monomers azurin, β-gal, and α-amylase
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