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At 1 M GdnHCl, one thiol group of GR became accessible to modification with 5,5'-dithiobis-(2-nitrobenzoic) acid (DTNB), whereas no changes could be detected in the spectroscopic properties (fluorescence, circular dichroism) of the protein
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In general, the autopeaks appearing on the diagonal in synchronous plots indicate that the intensity of the corresponding bands change with perturbation, whereas the crosspeaks show that the intensity changes of the two correlated hands are in the same (positive) or opposite (negative) direction
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These pretransitional conformational changes also resulted in an intermediate with hydrophohic exposure, which could lead to serious aggregation in both chemical denaturants and heat-treatment conditions
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The precipitate was resuspended m 6 M guanidinium hydrochloride (in 10 mM Tris buffer (pH 7
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It is also noteworthy that the observed scaling behavior is valid for a range of chain lengths that includes short chains (11)
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6, which shows that deviations from rodlike behavior occur for all sequence separations greater than a single residue
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9, which plots the probabilities, P^sub oa^(r = U), of finding cavities of different sizes at the ensemble-averaged center-of-mass as a function of cavity radius a
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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR
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The tetrameric enzyme has nine glycosylation sites per monomer, and carbohydrates account for ~25% of its dry weight
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This interaction perturbs the contacts that Gβγ makes with PLCβ, which causes enzyme activation
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1 B and by their independence of the scan rate), the heating and cooling curves of the apoA-2:DMPC complexes show hysteresis that was also observed in DMPC complexes with apoC-1 (Gursky et al
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The protofilament structure of insulin amyloid fibrils
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HE TALKS UP THE COUNTY'S DRUG DIVERSION PROGRAM, PARTLY TO SHOW THAT LAW ENFORCEMENT ISN'T TOTALLY HEARTLESS
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