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. To verity the results obtained in Fig
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. If S 0, the object is prolate
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. In this work we report a case study on five homologous α-amylases aiming to elucidate the impact of protein aggregation and conformational scrambling of the unfolded states on fluorescence emission
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. Although for BSA a high binding capacity may be expected from its intrinsic tendency to bind nonpolar and aromatic moieties also in the liquid state, the above ANS binding data do suggest that beyond specific trends of individual polypeptides, multi-subunit proteins are more susceptible than monomers to destabilization and partial unfolding in the frozen state
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. IENS is a technique sensitive to global hydrogen molecular dynamics on an Angstrom-nanosecond scale (depending on the instrumental energy resolution and angular range)
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. Wassink, Soldering in Electronics (Ayr, Scotland: Electrochemical Publications, 1984), pp
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. 5 ns with squared order parameter (S^sup 2^) of ~0
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. In CaM:bHLH interactions two flexibly bound complexes form a flexibly bound dimer of complexes, defining a geometric context and thereby increasing the number of interactions and thus leading to high affinity and specificity
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. The quantum yield of bound ANS is much higher than that for Bis-ANS, and the blue shift is more evident
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. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid
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. 34 K/min) suggest a small gradual reduction in the particle size below 80°C that parallels the CD changes at these temperatures (Fig
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. Then the many discrete steps of potential energy that arise from the sequence of "hypergutters" appear artificially close, and serve to create a funnel-like projected energy landscape
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. This illustrates case B (Fig
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. The case made it to a circuit court of appeals, which upheld a lower court's decision in favor of Port Chester, citing both a statute-of-limitations restriction and the precedent of Kelo v
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