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. [1] were (1) nucleation rates for LLPS and crystallization, (2) relative position of LLPS and crystallization temperature, (3) time provided by the thermal cycle for nucleation of phases during LLPS before nucleation of crystallization occurs, (4) relative positions of spinodal and binodal regions (nucleation rate of LLPS phases), and (5) growth of phases after nucleation (especially LLPS [1, 10, 15])
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.To see how this works, we suppose at first that the d ~ O(10^sup 2^) dimensions of the full folding space are now arranged sequentially so that diffusive searches in one dimension at a time allow the protein to find "gateways" into the next subspace (we will see how this may arise naturally in a physical way below)
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