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Decomposition of protein tryptophan fluorescence spectra into log-normal components
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Here, β = 1/RT, where R = 0
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Thermodynamic and folding properties versus structure among the members of a protein family Early studies suggested that folding and equilibrium pathways of homologous proteins were similar, and that the folding of a certain structure was thus conserved through evolution (58,59)
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6c and/or 5), establish whether fast exchange applies or not without prior knowledge of the exchange timescale
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In conclusion, residues with fast exchange can be identified from the combination of R^sub ex^ and ΔR^sub ex^ using either the fast exchange equations or the general fast/slow exchange equations derived by Ishima and Torchia (34)
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After 2 h, only very small aggregates (400 h), the protofibrils have increased in length to 100-200 nm, and the spherical clusters have decreased in size to 20-30 nm in diameter (Fig
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The pleckstrin homology domain of phospholipase C-β^sub 2^ links the binding of Gβγ to the catalytic core
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In these experiments, disk fusion coincided with the apoC-1 unfolding; in contrast, comparison of the corresponding CD and light-scattering data in Fig
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, 2003) and occurs above 50°C
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It is fascinating to think that nature custom-made proteins so that, when digested by gut enzymes, useful bioactive peptides result
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This unique ability of the four-way junction ribozyme to populate an undocked conformation with native-like structure (a quasi-docked state) likely contributes to its greater tertiary structure stability, with the quasi-docked state acting as an intermediate and facilitating the subsequent formation of the specific hydrogen bonding network during docking of the two loops
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The cells cultured in DMEM/ 10%FCS were associated with reduced extracellular matrix, as indicated by toluidine blue staining, when compared with pellets maintained in DMEM/ITS+/TGF-[beta]1, which stained metachromatically (Fig
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com has appointed Kathy Gersch vice president, chief marketing officer and general manager
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Medical schools use standardized patients to test students' diagnostic skills
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Despite all that, and the warning that whiskey and rock music would be the next targets, the industry fell before a vast coalition of liberals and conservatives, blacks and whites, who argued that some of those tykes were being left to roast alive in cars while their parents pumped their milk money into the poker machines
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