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. Runs were carried out at 23°C on a Shimadzu (Kyoto, Japan) LC-10AS HPLC at a flow rate of 0
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. The reference solutions corresponding to N, A, and UA states were prepared with HCl into water as those pH values become equal to 5
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. Stock solutions of guanidinium hydrochloride were prepared in 5 mM HEPES buffer, pH 7
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. Protein rSBA The recombinant form of the lectin was prepared according to Adar et al
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. In a previous study, we probed the role of the two proximal GlcNAc residues in tethering the glycans attached to one subunit to the side chains of amino acid residues of an adjacent subunit at the noncanonical interface (18)
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. How Aggregation and Conformational Scrambling of Unfolded States Govern Fluorescence Emission SpectraDuy, CABSTRACT In a case study on five homologous α-amylases we analyzed the properties of unfolded states as obtained from treatments with GndHCl and with elevated temperatures
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. 1, software for running the spectrometer and deconvolution and analysis of decays
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. Phospholipid-bound molecular rotors: synthesis and characterization
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. It is notable that although pressure techniques have been used to monitor the associations between aqueous soluble proteins, pressure has not yet been applied to monitor lateral associations of membrane-bound proteins (for recent reviews, see Ernst, 2002)
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. Role of dynamic interactions in effective signal transfer for Gβγ stimulation of phospholipase C-β2
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. coli lac repressor-operator interaction: kinetic measurements and conclusions
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. In species with age-structured spawning schedules, a broad age distribution will maximize the length of the spawning season
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. This result confirms that the sizable increases in E with Mg^sup 2+^ that we observe for the 2WJ (WT and SL) and SL 4WJ ribozymes are due to decreases in the interarm distances
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. (2-6) Approximately 80% of these weapons have muzzle velocities greater than 350 fps, and 50% have velocities of 500 to 930 fps
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. Federal authorities seize prescription drugs from distributorsThe Food and Drug Administration (FDA) and the United States Attorney for the District of Utah are announcing a series of indictments against multiple prescription drug distributors whose illegal distribution of diverted drugs could affect the safety and efficacy of more than 40 medications purchased by consumers in over 80 pharmacies nationwide
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. Medication Therapy Management is the single-greatest opportunity for pharmacy in more than 30 years," he said
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. A 2 (Gender: Male, Female) x 2 (Competitiveness: High, Low) ANOVA revealed no significant main effect of gender on extrinsic motivation, F (1, 74) =
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. Evidence of this deeper emotional involvement is indicated in the SOGS scores of the current study's seven participants whose scores indicate possible or probable gambling problems (e
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. IR (Infrared) suppressors were designed into the engines to channel ambient air into the exhaust that helps reduce the IR signature
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- , a professor of consumer finance at New York Law School in New York City
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.Midway through the concert, however, Cash took a chance that must have caused somebody to flinch
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. In their Medicare campaign, Alexander Strategy operatives also made creative use of nonprofits in a different way, this time employing a favored modus operandi of the DeLay era
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. RESULTS In this work, we focus on two-state proteins because the hypothesis is that only two well-defined macrostates-native and highly denatured states-are accessible to these systems (67-70)
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. This is a result of correlations that exist on all length scales and the fact that interactions that give rise to these correlations are purely repulsive in nature
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. For instance, we have shown that the thennodynamic folding parameters (ΔC^sub p^ and m-values) of the HPr of S
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. Circular dichroism CD spectra in the far-UV region (200-280 nm) were recorded on a Jasco J-810 equipped with peltier thermostating cuvette holder under constant nitrogen flow
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. Here, we compare the ANS binding capacity of the four azurin species to inquire how these modified features modulate the ice-induced perturbation of tertiary structure
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. Mechanisms of Ca2+-dependent transcription
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. Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, Thioflavine T
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.Structural polymorphism of mature fibrilsFig
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.How has such a remarkable reduction in folding time been achieved without the use of a spatially "funneled" energy landscape? Of course energetic interactions have been implied, but these have not been of the spatially-extended type
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.In 1937 an established pharmaceutical company, Massengill, killed 107 people by hawking a drug dissolved in anti-freeze as a flu treatment
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.Updating its annual "Combating Counterfeit Drugs Report, the FDA revealed May 18 it is pursuing several initiatives to further protect the safety and integrity of the U
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.The countdown clock on biogenerics should start ticking when regulatory guidelines are put in place
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.CHD, which buys the medications directly from manufacturers, purchases pharmaceuticals with discounts of up to 20 percent greater than what other vendors can provide, explained Clark
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.--Pharmaceutical SciencesUniversity at Buffalo School of Pharmacy and Pharmaceutical Sciences M
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.5K-674K Rental($15K-35K)TRANSMISSION REPAIR64 AAMCO Transmissions718/0$192
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