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37 million for the same 10-month period in 2005
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we used Metropolis Monte Carlo simulations to generate representative conformational ensembles in the EV limit
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Cornell University Press, Ithaca, NY
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From these findings it was deduced that the solidification of water affects the tertiary structure of azurin and it was suggested that binding of the fluorescence probe could represent a general approach to monitor ice-induced strains on the protein native fold
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The use of Xenopus oocytes for the study of ion channels
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Although it is known that parts of the insulin chains, such as the C-terminal of the B-chain, are not expected to participate in the tight intra- and interfibrillar packing (therefore giving rise to loose and soft elements protruding alongside the protofilament-Jimenez et al
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1) nested within the full high-dimensional search space
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A double row of minute melanophores along the ventral surface ended in a single melanophore at the constriction of the gut
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5-, 1-, and 2-ns block sizes) were used for fitting the standard errors to an exponential function using the xcrvfit software (http:// www
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Ribozyme constructs missing the substrate strand were prepared in annealing buffer (missing NaCl and supplemented with 12 mM MgCl^sub 2^) at a concentration of 2 µM of each strand and annealed by heating to 70°C for 2 min and cooling to ambient temperature
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The fluorescence emission was collected using the same objective, separated from the excitation light using a dichroic filter (540 DRLP, Omega Optical, Brattleboro, VT), spatially filtered using a 100-µ pinhole, and separated into donor and acceptor components using a second dichroic filter (630 DRLP, Omega Optical)
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001 NSAIDs 95%CIEffect of Type 1 RPCumulative effect over all months -$10,900,000-$4,098,872Cumulative effect per year -$1,505,318-$565,362Effect of Type 2 RPCumulative effect over all months -$24,800,000 -$20,600,000Cumulative effect per year -$4,378,332-$3,636,312Table 5: Effect of RP on Patient NSAID ExpendituresNSAIDs Estimate p-ValueEffect of Type 1 RPCumulative effect over all months $666,340
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In this collection of 11 articles, contributors describe their work in PTKs in such areas as using PTKs as targets for cancer and other indications, targeting Src homology 2 domains in drug discovery, using P12-kinase inhibition as a target for therapeutic intervention, using an activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia and JAK kinases in leukemia, lymphomas and multiple myeloma, applying platelet-derived growth factor, using a targeted therapy for myelogenous leukemia, testing signal transduction inhibitors in animal models of cancer, and using phosphoproteomics in drug discovery and development
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We had higher-than-anticipated usage in early January, which resulted in longer wait times and some stress on our inventory system," noted Toyota's Hesterberg
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GupchupThe purpose of this study was to examine the association between student-life stress and health related quality of life (HRQOL) among Doctor of Pharmacy (Pharm
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"Showing the cards"The World Series of Blackjack," a 13-episode series in which players compete for $1 million, currently airs on GSN, formerly known as the Game Show Network
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. As will be discussed below, we expect our results to be valid for the strict limit of maximally denatured proteins
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. Results for ubiquitin modeled as a freely rotating chain are shown in Fig
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. Why is one Bacillus alpha-amylase more resistant against irreversible thermoinactivation than another? J
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. This has been shown to alter the conformational stability of HuBChE (35), and to raise stability against thermal denaturation by 10°C from 63 to 73°C (18)
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. In the absence of internal motions slower than ~4 ns, (τ^sup o^^sub m^)^sub app-corr^ can thus be considered equal to (τ^sup o^^sub m^)^sub app^, the real overall tumbling time
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