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As previously pointed out (Rietveld and Ferreira, 1996; 1998; Ferreira and De Felice, 2001), dimerization may lead to a significant increase in stability against chemical modification of GR, including thiol oxidation, de-amidation, or proteolytic digestion
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INTRODUCTION Posttranslational modification is one of those events in biology that not only adorn a protein with variety but also impart it with different physicochemical properties
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However, the hemagglutinating activity and the carbohydrate specificity of rSBA are essentially identical to that of gSBA (19)
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Do harshly denaturing environments such as 8 M urea or 6 M GdnCl mimic perfect solvents? In previous work, we developed a fast and accurate way to generate thermal, self-avoiding distributions for proteins with atomistic detail (48)
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Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells
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They are active as dimers, where the two basic regions bind DNA symmetrically as α-helices on opposite sides in the major groove
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8, as usually seen in well-structured proteins
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Arrhenius plots in(τ) versus 1/T for the two kinetic phases where obtained from the relaxation times τ(T) measured at 70-95°C
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1 C, curves 2-4; Fig
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Sexual maturityParameter values for the length-maturity logistic model were [beta
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