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. The changes of thermodynamic parameters (enthalpy change ((Delta)H), entropy change ((Delta)S) and heat capacity change ((delta)C^sub p^)) corresponding to the transitions from N to MG (molten globule state) or MG to U (unfolded state), were summarized in the previous report (Nishii et al
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. The gene mapping showed that at least three genes, on three distinct chromosomes, affect eye development, though the exact roles of the genes are still unknown
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. DSC was used to investigate whether the thermal denaturation of ACYI was reversible or not
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. Interestingly, the difference in T^sub m^ of the two forms is ~26°C, and this estimates the extent of stability imparted by the oligosaccharide chains to the stability of gSBA
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. Understanding protein folding via free energy surfaces from theory and experiment
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. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8M urea
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. AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR
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. Diminazene peaks were not observed within 6 h, whereas aceturate peaks slowly grew with time
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. We interpret these results such that although diminazene penetrates the cell membrane earlier than aceturate due to higher permeability, a large portion of it is strongly bound, and only a small portion of diminazene molecules weakly bound to nuclear macromolecules gives the initial signal
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. The ^sup 15^N-{IH} nuclear Overhauser enhancement (NOE) shows only weak field dependence and was therefore only earned out at the higher field
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. To facilitate direct comparison of the CD and DSC data in Fig
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. For example, a nonnative attraction beween the helices irrespective of their axial orientation would favor a two-dimensional search out of contact before a three-dimensional search in contact as the structure of the five-dimensional search space
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. The framework and specific examples discussed here suggest useful coarse-grained models of other families of proteins that may be simulated very efficiently, or even approached analytically, as we have done with the three-helix bundles
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. Greater densities (>20 larvae/10 [m
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. Unlike the majority of interstellar clouds, which serve as nurseries for new stars and measure some 10 to 30 light-years across, most cemeary globules span only about one-tenth that distance and lack sufficient gas and dust to form stars
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. We have successfully produced monoclonal antibodies to differentiate harmful marine phytoplankton species from morphologically similar harmless species (Hiroishi et al
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