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. In the Arrhenius plot (Fig
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. (46) used pulse-field gradient NMR to quantify effective hydrodynamic radii for seven denatured proteins, the lengths of which varied from 16 to 247 residues
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. NOE values were determined from pairs of spectra recorded interleaved with and without a 4-s proton saturation (see Supplementary Materials, Table RS1, for more details)
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. The S^sup 2^^sub s^ was either kept at a uniform constant value (M2I) or optimized together with τ^sub if^ and S^sup 2^^sub f^ (M2II)
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. In conclusion, we have shown that insulin amyloidogenesis in vitro induced by the en masse destabilization of native dimers proceeds through a multipathway assembling scheme, which employs-on the one hand-the hierarchical intertwisting reported earlier; and on the other hand, employs lateral interactions of single particles and fibrils, leading to larger domains of features aligned in parallel (Fig
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. The cooling path for our non-equilibrium TIPS process is indicated by (1) [arrow right] (2), and the cooling rate is about 12 to 26°C/min near the cloud points
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. Age (yr)FL (mm)Maturity stageMonth range range range nMarch7-25375-5101, 4-610April7-18364-4471, 5-612May7-13340-465 1 and 615June 5-13349-432 1 and 615July 5-13360-475 1 and 614August 5-11357-4931-2, 615September6-16366-488 1 and 212October5-16357-420 1 and 211November 5-11355-434 1 and 216December 5-14365-439 1 and 210January6-17369-473 1-416February 7-17378-464 1-517March6-13380-4671, 5-612Table 3Age group-specific absolute fecundity (based on fertilizedeggs) and age distribution of mature females as a percentageof all mature females, used to estimate larval production
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