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. In this work, we further investigate the stability and structure of El^sup sc^ at different pH in the absence and in the presence of its effectors (PEP and Mg^sup 2+^)
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. a sigmoidai curve with a pK^sub a^ of 4
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. Am J Respir Cell Mol Biol 2001; 24:608-615(42) Golpon HA, Fadok VA, Taraseviciene-Stewart L, et al
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.There are no conflicts of interest for any of the authors
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. In the last decade, strong binding of ANS to molten globule states of proteins has been linked to the loss of tertiary structure (7), and since then the method has been applied to characterize transient states in protein denaturation (8-11)
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