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Similarly to that observed for EIC^sup ec^, the electrostatic, as well as the van der Waals interactions, were decreased in EIC^sup sc^, losing several salt bridges and hydrogen bonds when compared with the structure of EIC^sup tt^
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. However, upon unfolding transitions generally distinct shifts of the emission spectra are reported (see for example (4,9-14))
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. The backbone (N, Cα, and C') atoms of individual residues were used for superposition of trajectory configurations when calculating the entropy per residue (code: fir)
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