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. From the difference contact maps, we find that upon folding, specific nonnative local contacts have to be broken (weakened) to make native, nonlocal spatial contacts
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. Simulated data agree with theoretical predictions and the agreement is quantified in tenus of residuals between the theoretical distribution and those from simulations
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. Protein concentration was 4 µM, unless otherwise indicated
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. As a representative for the first class, BLA shows a λ^sub max^-value for the native state of 333 nm, which increases up to 339 nm upon thermal unfolding
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. Magnetic Resonance Imaging: Physical Principles and Sequence Design
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. This latter observation has been ascribed elsewhere to contributions to the scattering signal from the hydration water protons, which are more flexible than protein protons in the temperature range above 260 K (44)
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. In contrast to the interior, pressure has little effect on the membrane surface charge (Scarlata and Rosenberg, 1990)
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. Although the exact shape of this transition varies for apoA-2 samples from different plasma pools, the sharp peak at 24°C is always observed after disk heating beyond the high-temperature DSC transition, indicating disk-to-vesicle conversion in this transition
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. 1 C, curves 2-4; Fig
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