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Piper Professor of Biblical Theology at Princeton Theological Seminary
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It was difficult to distinguish in this research whether the pretransitional changes occurred in the catalytic domain or the dimerization domain of ACYI
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Correlated fluctuations give rise to ensembles that are characterized by a range of internal cavities
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However, the absence of native baseline at low temperatures did not yield reliable results when fitting the data to Eq
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Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells
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For instance, the barnase (45) and oxalocrotonate tautomerase (46) bind specifically to their rigid target to form a specific complex with essentially one overall conformation
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The solubility of lactoglobulin in dilute solutions of sodium chloride at varying ionic strength and hydrogen ion activity
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RESULTS AND DISCUSSIONCharacterization of soluble prefibrillar aggregates and protofibrilsGeneration of prefibrillar oligomers of TTR from the A-stateProlonged dialysis of TTR (96 h, 4°C) versus 10 m M HCl in dH^sub 2^O in the absence of salt (pH 2
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Thus, the fast unfolding phase is observed in disks and in the mixture of lipid-poor and vesicle-bound apoA-2, whereas the slow unfolding phase is observed in disks only
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Therefore, throughout the following overnight dry incubation period no further structural transitions are likely to occur in the amyloid samples
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This is significant for the topomer search model: we might expect to find departures from the folding time/ contact order correlation when, despite sharing the same topology of fold, one protein in a pair has an important diffusional subspace stabilized whereas the other does not
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Thus, within the framework of these simulations and the two-state model, we can estimate the forward rate constant (k^sub 1^) for the extended-undocked to quasi-docked reaction to be in the 10 × 10^sup 3^- 41 × 10^sup 3^ s^sup -1^ range and the reverse rate constant (k^sub -1^) in the 3
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3-6 Here, we report our experience with the role of the autocrine loop using TGF-[alpha] and EGFR immunohistochemistry in formalin-fixed tissues from malignant pleural mesotheliomas and reactive mesothelial proliferations
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