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. The author profiles companies such as Amgen, which has made a success by bringing Epogen and Neupogen, artificial versions of naturally occurring enzymes, to market during the past 20 years
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. This work was supported by a grant from the Dept
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. , the average overall 10^sup 4^ conformations, was used to compute the average Kratky profile
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. 5 b, but was also observed for all other α-amylases which otherwise exhibit aggregation upon thermal unfolding
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. Model selection, order parameters, and timescales for internal motionBased on the qualitative analysis of the RT^sup n^^sub 1^ versus NOE plots, Fig
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. 5 in the presence of 80% glycerol clearly shows pH-independent fluorescence (Fig
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. Membrane binding of the G-protein subunits was followed by changes in the fluorescence of the CPM-labeled proteins (see Philip and Scarlata, 2004)
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. These naturally belong to the levels of coarse-graining at which we treated the helix bundles above
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. It is clearer in experiment than the subsequent dimensional reductions because it is the only one that makes significant changes to the radius of gyration of the protein
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. S rangeYearIchthyoplankton surveys1978-79 42[degrees]27'-45[degrees]30'198235[degrees]55'-40[degrees]53'198338[degrees]30'-44[degrees]32'198544[degrees]41'-46[degrees]52'198641[degrees]34'-44[degrees]36'43[degrees]01'-46[degrees]50'199135[degrees]49'-36[degrees]51'199541[degrees]16'-45[degrees]22'199642[degrees]29'-44[degrees]01'199842[degrees]21'-45[degrees]36'199943[degrees]21'-44[degrees]01'200043[degrees]19'-46[degrees]24'200143[degrees]19'-46[degrees]54'42[degrees]54'-45[degrees]25'42[degrees]21'-43[degrees]42'Posttransition juvenile trawls199242[degrees]04'-45[degrees]43'199843[degrees]18'-47[degrees]02'199943[degrees]10'-47[degrees]01'200043[degrees]45'-47[degrees]02'200142[degrees]54'-45[degrees]25'Long
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. The system includes application of bioinformatics--it is not simply a library but an interpretive tool
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. The peak positions for the SL 2WJ and 3WJ constructs closely follow the trends observed for the undocked peak with the corresponding WT constructs, confirming that removal of the loop on arm A provides appropriate models for the undocked states of the WT ribozymes
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. This result confirms that the sizable increases in E with Mg^sup 2+^ that we observe for the 2WJ (WT and SL) and SL 4WJ ribozymes are due to decreases in the interarm distances
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. Furthermore both types of samples exhibit associated fluorescence emission spectra that are rather similar
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. These observations are consistent with reports of the solidlike behavior of relatively dilute globular protein solutions (0
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