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The change of the intensity at 330 nm could not be fitted to a simple two-state model, and a platform could be found at the temperature range of 52°C-60°C (Fig
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The phase diagram analysis, which is a sensitive tool to detect folding intermediates (35), was performed to characterize whether an intermediate was involved in ACYI thermal unfolding
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Table I lists relevant information for the 23 protein sequences (68) used in this study
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Urea promotes polyproline II helix formation: implications for protein denatured states
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1% of the residues in the most favorable regions and 10
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With respect to corresponding CD spectra we observed for both types of samples (i
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Determination of atomic mean-square displacementsThe elastic intensity (Eq
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We refer to these plots in the following as Guinier plots, due to their analogy to the Guinier plots in SAS
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03 M NaCl and adjusted to the required pH with dilute NaOH
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Interestingly, amyloid deposits can also be found in prion diseases, suggesting a common link between these diseases
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It is generally accepted from thermodynamic and biochemical data that the β-sheet of gp120 that bridges the inner and outer domain of the gp120 core, the bridging sheet, is only fully formed and stabilized upon complexation with CD4 (Fig
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With fluorescence microscopy with B-exciting light, yellowish fluorescein coronas around the cells of the toxic species were observed, confirming a positive reaction
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7 These methods have generally led to the formation of fibrocartilage, which has limited functionality compared with hyaline articular cartilage
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"This is a one-two punch aimed at the same community pharmacists who U
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These findings suggest that where monetary gain is both literally and symbolically possible, gender differences in the driving force behind participation are likely to be found
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