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Says Stratigos, "[Greg] and I looked at each other, and that was the sign from the universe
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The software is called Ring Factory, and after downloading it into a PC or Mac, users can create a ring from any part of a favorite song, as opposed to just the first few notes of a song
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Taken together, these results suggest the existence of two molten-globule-like intermediate species (one dimeric and one monomeric) in the unfolding of GR
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Fully unfolded monomers were obtained at higher concentrations of GdnHCl
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Flory showed that a quantity such as the average radius of gyration (R^sub g^) will scale with chain length (N) according to a power law of the form R^sub g^ = R^sub o^N^sup ν^ (45)
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Cavity statistics, P^sub oa^(r) folded ubiquitin are shown in Fig
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These results would make sense if denatured-state topologies were equivalent and invariant with sequence
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Analysis of difference contact maps suggests that to fold, the dilatation symmetry in the EV limit is broken by weakening specific nonnative local contacts
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The role of long-range forces in the phase behavior of colloids and proteins
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Therefore, the widely accepted correlation between cation binding and compaction potential is not an absolute
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This protofilament + monomers/ oligomers scenario is an alternative pathway to the otherwise dominating protofilament + protofilament way of the protein fibrils' lateral growth
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Another example of this projection is found in the master-equation approach (Zwanzig, 1995), in which the smoothly funneled high-dimensional energy landscape implies some shaping of the nonnative contacts of the underlying model
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This precisely exemplifies the general mechanism we have suggested, with the additional feature that one of the hypergutters has become so stabilized (and therefore so populated) that it attracts the label of "intermediate state"
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Temporal patterns in parturitionFrom 1996 through 1998 we estimated relative larval production for four age groups: 6-8; 9-11; 12-14; and 15 years and older (Fig
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) Ford EG, Senac MO, Jr
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(Shown above in Beyond the Dream, Beyond the Sun and Beyond the Moon
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As economists Daniel Klein and Alexander Tabarrok state in FDA Review, their Web site recounting the history of the agency, "Licensed doctors
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2] receptors in a group of monkeys' brains using positron-emission tomography (PET)
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Xavier's premed program is consistently ranked top 10 in the country and its graduates usually have their pick of medical schools
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In the United States, the practice is out-and-out illegal; in Canada, it "raises legal, ethical and public policy issues," reads the joint statement
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On track to add an estimated 250 new supercenters by the end of its fiscal year in late January, Wal-Mart is positioned to surpass for the first time annual sales of $200 billion from its domestic stores division
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curriculum has not been reported
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Higher scores on this inventory represent more stress
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. Here, [left angle bracket]R^sup 2^^sub e^[right angle bracket] is the mean-squared end-to-end distance, R^sup 2^^sub ij^ = |r^sub i^ - r^sub j^|^sup 2^, and we choose r^sub i^ and r^sub j^ to be the position vectors of α-carbon atoms of residues i and j, respectively
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.0 (dashed τ^sub if^ contours and solid S^sup 2^^sub f^ contours)
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. Particle diameters were assessed from comparison with protein markers with known Stokes radii and were confirmed by EM measurements
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