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Moreover, resolution-enhancing techniques, such as second derivative and 2D IR, have been shown to be sensitive tools to monitor the sequential events in protein conformational changes by FTIR (27,28,30,38-42)
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In the folded form, the average packing density is high and protein interiors are thought to he either solidlike (87,88) or like "randomly packed spheres near their percolation threshold" (89)
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Tran and Rohit V
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These changes were probably due to a histidine residue, which titrates in that pH region (43)
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CHRONIC INFLAMMATORY DISEASES OF THE LUNGImpaired efferocytosis is associated with a variety of chronic lung diseases, including cystic fibrosis (CF), non-CF bronchiectasis, COPD, asthma, and idiopathic pulmonary fibrosis (H
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All fluorescence spectra were corrected for background scattering as measured with pure buffer
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5), which is necessary for the glutaraldehyde reaction
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5, A and B, show a correlation between the protein folding/unfolding and the changes in the particle morphology
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In general, the lateral binding seems to be highly variable
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Other potential experimental sources of broadening, such as dark states or photobleaching, are not considered in these simple simulations
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For the 2WJ, some folding is observed in the absence of loop A, although the molecule does not form a stable quasi-docked conformation with arms A and B in close proximity
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He and his coauthors caution that the method has a long way to go before it can be used in people
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The increase in abuse of prescription painkillers by teens has been slight but at a persistent level of high use
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"Lack of diversity in the makeup of the subjects and researchers in clinical trials limits the ability to address and eliminate health issues
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Over half the faculty positions had been vacant because there were not enough eligible candidates to fill the positions
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In fact, most retail pharmacies now offer customers a 90-day refill option
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"If he's not successful in opening a gaming operation in Detroit, Barden hasn't ruled out the possibility of moving his headquarters out of the Motor City
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It's similar in tone and outlook to Ben Mezrich's recent Bringing Down The House, about a team of blackjack sharpies from the Massachusetts Institute of Technology
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A hero in the war abroad, he found himself embroiled in just as deadly a war at home, for at the time of his enstatement the Mafia had corrupted Louisiana's government
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. In C3A/C26A the elimination of the superficial C3-C26 disulfide bridge, linking the ends of strands β land β2, has little effect on the compactness of the protein core and, judging from the phosphorescence properties of W48 embedded in it (18), internal motions remain restrained
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