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Compact state of a protein molecule with pronounced small-scale mobility: bovine alpha-lactalbumin
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1-cm path length cuvette on a Jasco spectropolarimeter 715 (Jasco, Tokyo, Japan) attached to a Peltier PTC-348 WI
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5 M were monitored using tryptophan fluorescence
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While this may well be due to the enhanced induction of apoptosis, increasing data suggest that the clearance of dying cells is also impaired
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Due to a tight sealing of the quartz cuvettes temperatures of protein solutions up to ~120°C were applicable without evaporation and boiling
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Interestingly, the characteristics of spectral shapes as observed for BLA and PPA appear rather similar, although BLA shows a red shift and PPA a blue shift upon thermal unfolding
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A fluorescent probe of nonpolar binding sites
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Since the dealkylated soman moiety bound to the HuBChE monomer subunit contributes only three hydrogen atoms (P-CH^sub 3^) to the enzyme-inhibitor conjugate, while the deglycosylated native enzyme monomer itself accounts for >3500 nonexchangeable hydrogen atoms, the contribution of the inhibitor is negligibly small
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As a result, the small size of a hydrated cation provides effective interaction with DNA due to higher Coulomb electrostatic potential (Rouzina and Bloomfield, 1996) and the possibility of being incorporated into the DNA minor groove (Bartenev et al
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These diseases include the amyloidoses such as Alzheimer's disease and familial amyloidotic polyneuropathy (FAP)
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Fluorescence spectra were obtained from samples in quartz cuvettes with 10 mm or 4 mm pathlengths
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The hypergutter picture is also related to the topomer search model
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Ovary wallbe visible
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Notes: The bold values indicate period-specificaverage monthly rates relative to rates in thepre-RP period
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