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The quaternary structure of GR in the presence of GdnHCl was also investigated by size-exclusion liquid chromatography
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The resultant data are used to compute P^sub oa^(r), which is defined as the probability of linding a cavity of radius a at a distance r from the center of mass in the ensemble
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In principle, unfolded states are rather heterogeneous (26-28) and in addition the mechanisms leading to unfolded states are rather different for thermal and GndHCl-induced unfolding (1)
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Delivery of drugs across cellular membranes is one of the main goals of current pharmaceutical research (43), including MRI contrast agent development for biological applications (44)
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2 shows that the MSDs for the two enzyme samples are identical, within experimental error, over the whole temperature range measured (20-285 K)
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The average disk diameters were determined from EM images with an accuracy of 0
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1, A and B), confirm that cold denaturation is an intrinsic property of the marginally stable S-S linked apoA-2 dimer
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Truncated staphylococcal nuclease is compact but disordered
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MeasurementsCloud points for IPP in Isopar G were determined visually (Figure 2)
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44)Physical Componentof HRQOL 51
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