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. Three-point calibration of lhe pH-meler was performed by using slandards from Radiometer
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. We observed that at physiological pH as the concentration of protein was increased, the value of K^sub sv^ was reduced: 1
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. 2 K; 4 µM, T^sub m^ = 329
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. In the usual space-time windows of IENS experiments, this represents dynamics of larger atomic groups such as protein side chains (3)
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. At physiological temperatures, atomic mean-square displacements (MSDs) measured by IENS reflect sampling of conformational substates (entropy) as well as vibrational amplitudes
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. RESULTSMeasurement of protein-membrane associations under pressurePrevious studies of model membranes underpressure suggest that the primary effect of pressure is in the compressible hydrocarbon region, and the application of pressure increases the gel to liquid crystal phase transition by a constant that depends primarily on the lipid chains (Li and Kay, 1977)
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.Thus, the effective size of the monocation in compact DNA is expected to be closer to the size of free ion without hydration shell, where the sequence of the monocation radius is Li+ CONCLUSIONOur investigation highlights the inverse relation between DNA compaction potentials of monovalent cations in a crowded environment and the previously reported DNA binding properties of different alkali ions
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. Evidently increasing viscosity increases the quantum yield of DCVJ (Fig
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. For proteins containing N residues, there are of order N^sup 2^ nonnative interactions that may be encountered during a diffusive search, but only of order N interactions that define the native state
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