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Investigation of the properties of these partially folded states using probes such as ANS or bis-ANS (which bind to exposed hydrophobic domains in proteins) was not possible due to the significant overlap between the emission spectra of these probes when bound to proteins and the excitation spectrum of the prosthetic group, FAD (data not shown)
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The static magnetic field dependence of chemical exchange linebroadening defines the NMR chemical shift time scale
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An alternative explanation is that in this concentration range, the presence of an interfacial layer of protein has a marked influence on the observed rheology
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The infrared spectra of the amyloid suggest a parallel arrangement of the β-strands (Bouchard et al
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Φ-Values: normative contributionsAs a second general prediction, and as an example of the specific calculations possible with the model, we examine the important question of Φ-value analysis and its interpretation
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Folding dynamics of the B1domain of protein G explored by ultrarapid mixing
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Analysis of combined trajectories can yield information on the difference in the conformational spaces visited by the two trajectories, e
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