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The fully deuterated samples were obtained by incubating the protein solutions in a water bath at 50°C for 15 min, and then the samples were cooled to room temperature and lyophilized
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Specifically, we ignored the interactions between atoms in residues whose C^sub α^-C^sub α^ distance exceeds 15 Å because the inverse power potential energy for these distances is nearly zero
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For large x, entropy opposes stretching of the chain beyond its average value of R^sub e^
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In CaM:bHLH interactions two flexibly bound complexes form a flexibly bound dimer of complexes, defining a geometric context and thereby increasing the number of interactions and thus leading to high affinity and specificity
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However, the PLCβ^sub 2^ N-terminal PH domain allows for full activation by Gβγ-subunits (Wang et al
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To determine whether this could be the case for PLCβ^sub 2^, we monitored the change in emission of CPM-PLCβ^sub 2^ under pressure
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A thorough examination of these initial forms is of interest, as in this early timescale of the aggregation process both the nucleation and elongation coexist, and may influence each other
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There were also differences in the frequency of positive immunostaining with EGFR in both reactive mesothelial proliferations and mesothelioma, but in this instance the differences achieved a level of significance (P COMMENTTransforming growth factor [alpha] is a mitogenic protein that shares significant homology with epidermal growth factor
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) Harris W, Luterman A, Curreri PW
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[FIGURES 2-3 OMITTED]Multiplying the price reductions attributable to the introduction of RP by the quantity of NSAIDs dispensed post-RP produced (undiscounted) total savings estimates of $7
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