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. The implication is that EV-limit ensembles for proteins are likely to be close facsimiles of conformational ensembles in high concentrations of chemical denaturants
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. A summary of our results from analysis of EV-limit ensembles for 23 different two-state proteins is provided below: 1
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. Our approach is different because we use a single potential function to capture both local structure and nonlocal fluctuations
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. Protein was extensively dialyzed against 2 L of the working buffer (5 mM HEPES buffer containing 10 mM NaCl and 2 mM β-mercaptoethanol, pH 7) at 278 K
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. The fact that the HuBChE preparation is a tetramer, whereas the DmAChE preparation is a dimer, does not find expression in a difference in their global MSDs
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. semifasciata on the base of the caudal fin upper lobe (Herrera and Cousseau, 1996) was already present (Fig
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. The low number of positive stations in spite of the intense sampling conducted within the area of distribution of P
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. In An egg production method for estimating spawning biomass of pelagic fish: application to the northern anchovy (Engraulis mordax) (R
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. This increase, however, only amounts to Due to the large number of atoms of gp120, the conformational sampling is not yet complete within the 8-ns simulation
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. It is generally accepted from thermodynamic and biochemical data that the β-sheet of gp120 that bridges the inner and outer domain of the gp120 core, the bridging sheet, is only fully formed and stabilized upon complexation with CD4 (Fig
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. Exp Cell Res 1992:200:379-92
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