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This suggests that the exposure of one SH group in the presence of 1 M GdnHCl is due to an ionic strength effect
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In the fully extended conformation, the chain is loosely packed because it is maximally stretched
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Contrary to interpretations of many such experiments, numerous molecular simulations (7,23,99) and recent single-molecule experiments (75) provide little evidence of long-range residual structure under harshly denaturing conditions
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This work was supported through the core strategic grant of the United Kingdom Biotechnology and Biological Sciences Research Council
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The existing morphological studies on insulin aggregation stress the hierarchical intertwisting of protofilaments (Jimenez et al
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Interestingly, the clusters are not spherical, and pearl-like arrangements and elongated forms appear to dominate (examples are marked in Fig
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THERMAL ANALYSISWe determined the crystalline melting temperatures T^sub m^, of the IPP, EVA 9%, and EVA 19% polymers by DSC as 165, 83, and 97°C, respectively
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