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The MG concept was introduced to describe the properties of partially folded intermediate states sharing similar structural characteristics (i
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1), and undergoes a progressive red-shift with increasing concentrations of GdnHCl
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However, we cannot rule out that an alternative explanation to the titration curve is that the deprotonation of a histidine residue can be felt by a residue(s) far enough in the three-dimensional structure (see Fersht (45) and references therein) affecting its (their) environmcnt(s)
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Proteins of the phosphoenolpyruvate:sugar phosphotransferase system in Streptomyces: possible involvement in the regulation of antibiotic production
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3 mm inner diameter (Wilmad-LabGlass, Buena, NJ)
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The large-amplitude relocalization of the V3 loop of gp120 upon binding is, however, free from any substantial entropic cost
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Truncated variants of gp120 bind CD4 with high-affinity and suggest a minimum CD4 binding region
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Almqvist KF, Wang L, Wang J, et al
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