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Thus, we confined our study to a cell system with intracellular compartments larger than the smallest voxel dimension we could realistically obtain
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Large-scale purification and long-term stability of human butyrylcholinesterase: a potential bioscavenger drug
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The PLC-γ1 C-terminal SH2 domain (19) and Csk SH3 domain (47) bind specifically to their flexible (peptide) target to form a specific complex, again with essentially one overall conformation
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This is a common be havior of protein phase diagrams and of particles with shortranged attractive interparticle forces, e
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DCVJ, a molecular rotor, was employed for the first time for studies of an amyloidogenic process and is shown useful for detection of the early steps of the oligomerization process
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Bound to aggregated TTR, the fluorescence lifetime of both components have increased and the relative amplitude of the slower component has increased (Table 3), well in accordance with the massive increase in quantum yield compared to when bound to native TTR (Fig
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The remarkable size may result from both the number of monomers involved, and the fact that insulin aggregation intermediates are rather bulky and swollen with water (Dzwolak et al
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Simple versions of these models have indeed been able to account rather well for folding rates as a function of secondary structure formation (Myers and Oas, 1999, 2001)
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Rationalization of this observation has given rise to a third view of the critical pathway of protein folding, the "topomer search" model (Plaxco and Gross, 2001)
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Aspectos ecologicos y pesqueros del "salmon de mar" Pseudopercis semifasciata (Cuvier, 1829) (Osteichthyes, Pinguipedidae) en aguas norpatagonicas
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The large-amplitude relocalization of the V3 loop of gp120 upon binding is, however, free from any substantial entropic cost
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In terms of frequency, there were differences in the immunostaining with TGF-[alpha] in both reactive mesothelial proliferations and mesotheliomas, but these differences did not achieve a level of significance (P =
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Great Horned Owls, in particular, show a propensity to crush the bones of their prey prior to ingestion, making them more susceptible to chemical dissolution (Dodson and Wexlar 1979, Duke et al
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