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These changes, however, have positive effects on the interest of potential male research participants
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Each data point was an average of four accumulations
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This erroneous model is of interest only because it has been used previously for denatured proteins in studies aimed at correlating m values and ΔC^sub P^ to changes in solventaccessible surface area (90)
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, at the tips of the N- and C-terminal domains, ii), close to the hinge region connecting the N- and C-terminal domains, iii), close to the hydrophobic pockets in the N- and C-terminal domains where the target binds (see Fig
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9), the change in viscoelasticity is a further indication of the onset of a glass transition with increasing BLG concentration
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7, with background corrected from unbound probe
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Our main goal with this study was to employ a variety of fluorescence probes (ANS, Bis-ANS, DCVJ, and ThT) and techniques (steady state and time resolved) to recognize and characterize different states of a protein in the process of misfolding and self-assembly
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Abbreviations used: LpA-1, HDL containing apoA-1 but not apoA-2; LpA-2, HDL containing apoA-2 but not apoA-1; LpA-1/A-2
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The unfolding rate increases at higher temperatures, indicating high enthalpic contribution ΔH* to this barrier
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Recently, ideas as to the generic, polymeric character of amyloids (Fändrich and Dobson, 2002), and the importance of destabilization (or complete unfolding-e
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For a molecule existing in two different states but with similar atom-positional fluctuations, similar configurational entropies are expected for the two states
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Atomic insight into the CD4 binding-induced conformational changes in HIV-1 gp120
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The inability of two- and three-way junction ribozymes to fully populate a docked conformation reveals the importance of correct helical junction geometry as well as loop elements for effective ribozyme folding
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The peak position for the SL 3WJ remains in the low-FRET region of the histograms, independent of the Mg^sup 2+^ concentration, indicating that this ribozyme construct is incapable of folding to a compact structure (Fig
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Will this work and is it safe? If it is safe, what would you estimate the velocity and accuracy to be? Would leading be a big problem? And at what distance would you set the target and pellet trap?D
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Histology and electron microscopy confirm these findings, indicating that pellets maintained in DMEM/ITS+/TGF-[beta]1 possessed an extensive extracellular matrix (Fig
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White currently is working with Rachel McAdams in the upcoming film "The Family Stone
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She also said she would propose a session on best pharmacy practices to encourage the profession to share new ideas and solutions
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lawmakers either to enforce the laws already on the books or to write new legislation banning the cross-border pharmaceutical trade
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06 paid by third party plans
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We also wanted to try to help pharmacists better understand and communicate information about the new Medicare Prescription Drug Benefit to facilitate conversations with beneficiaries and to help them reach out in the community
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