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. Apart from its crucial functions in intracellular amino acid metabolism, ACYI also has substantial commercial importance for the optical resolution of N-acylated DL-amino acids
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. The Kratky profiles reveal the presence of three distinct regimes for each sequence
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. Although the exact shape of this transition varies for apoA-2 samples from different plasma pools, the sharp peak at 24°C is always observed after disk heating beyond the high-temperature DSC transition, indicating disk-to-vesicle conversion in this transition
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. Alternatively, our picture suggests ways of increasing folding times greatly by selective mutations that retain topology and stability of the native state, but destabilize one or more of the on-pathway diffusional subspaces so that intermediate searches are required in d > 3
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