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A growing number of pharmacists have been refusing to dispense birth-control pills and emergene/contraception (ECP) because it goes against their personal beliefs--and the law allows it
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The column was then washed extensively with PBS till the washings had A^sub 280^Isothermal guanidinium-hydrochloride-induced denaturation Equilibrium unfolding as a function of guanidinium hydrochloride (GdnCl) concentration was monitored by fluorescence spectroscopy
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RESULTS In this work, we focus on two-state proteins because the hypothesis is that only two well-defined macrostates-native and highly denatured states-are accessible to these systems (67-70)
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The science surrounding an understanding of the biological basis of each individual and its relationship to all the elements of its environment continues to march forward at an ever-quickening pace
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The two cytoplasmic regions differed in their lipid contents and NMR lineshape characteristics-differences that are not detectable with whole-cell NMR techniques
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INTRODUCTIONCalmodulin (CaM) is a Ca^sup 2+^ binding protein, present in all eukaryotic cells
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Early diagnosis of amyloid disease is extremely difficult
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This analysis can potentially allow us to discriminate between A-state monomers, protein oligomers, and larger aggregates
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Three probes-ANS, DCVJ, and ThT-show increased fluorescence throughout the aggregation reaction, whereas Bis-ANS shows fluorescence decay (Fig
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ANS binds to a small extent to the unfolded monomeric form of TTR (Table 2), providing an excellent reference point for molecular dynamics studies of the quaternary structure of TTR
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4 acting as lateral scaffolds for formation of following fibrils, which at the same time ensures ordered, parallel organization of large domains of fibrils
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How has such a remarkable reduction in folding time been achieved without the use of a spatially "funneled" energy landscape? Of course energetic interactions have been implied, but these have not been of the spatially-extended type
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1975, 1976; Fuller and Duke 1979; Marti 1973), and remains of a single prey can end up in multiple pellets (Lowe 1980)
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Pharmacy at the end of their first quarter was up 29 percent versus last year, while front end was up 32 percent
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1 million for the year-ago period
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Most of the conference's organizers are Methodists like Grey, and a majority of attendees are Christians of one sort or another
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. Denaturation of the native enzyme is reflected by a relative increase of MSDs consistent with entropic stabilization of the unfolded state
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.[FIGURE 1 OMITTED]Histological preparations were made from the ovaries of 175 females collected monthly from March 1996 through March 1997 to track seasonal ovarian development
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. After removing the PBS, 200 [micro]L of the hybridoma culture supernatant solution was added to the wells and incubated at room temperature for 30 minutes
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