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. (11), we obtained a scaling exponent of v = 0
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. Upon dimer formation, the higher pail of the groove, formed by the helix-loop-heiix motif and the rest of the protein (and which traps Tip^sup 461^, was partly fixed by the other monomer via several salt bridges, thus bumpering solvent-accessibility to the indole moiety
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. 2-4, the osmotic pressure determined using the osmotic stress technique is plotted as the dimensionless compressibility factor, Π/ρk^sub B^T, as a function of protein mass fraction for pH 8
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. Relaxation functions in folding kineticsWe first take a very simple case: if the nonnative gutter-stabilizing interactions are perfectly balanced with the entropy changes at each stage of the dimension reduction, then the free-energy profile is itself flat, and the d diffusive dimensions form an effective one-dimensional path along which the folding takes place
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. The I [arrow right] A transition, which was referred to as the dominant unfolding process above, began at around 70°C and the midpoint of the transition (T^sub 1/2^) occurred at ~84°C (see Table 1)
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. The two cytoplasmic regions differed in their lipid contents and NMR lineshape characteristics-differences that are not detectable with whole-cell NMR techniques
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. We conclude that functional differences arising from these structural differences are either of a local nature (e
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